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Your Guide To Polyendocrine Metabolic Ovarian Syndrome

PMOS, also known as Polyendocrine Metabolic Ovarian Syndrome, is a common condition that causes hormonal imbalance and affects how a woman’s ovaries work. It affects 1 in 10 women and around 70% of people with PMOS don’t actually realise that they have it.

What Causes PMOS?

PMOS is linked to hormone imbalances, particularly involving insulin levels.

Many women with PMOS are resistant to insulin, meaning their bodies don’t respond to insulin as effectively as they should. To compensate, the body produces extra insulin, which can then trigger higher levels of hormones like testosterone.

What Are The Main Features of PMOS?

Irregular periods – this happens when your ovaries don’t release eggs regularly (ovulation). As a result, your cycle may be unpredictable, very light, or sometimes absent altogether.

Excess androgens – these are higher levels of “male” hormones, like testosterone. They can cause symptoms such as acne, unwanted facial or body hair, or even hair thinning on the scalp.

Polycystic ovaries – this means the ovaries are larger than usual and contain many small fluid-filled sacs (follicles). Despite the name, they aren’t actually cysts, but immature eggs that haven’t developed properly.

What Are The Symptoms Of PMOS?

PMOS is characterised by a combination of symptoms and these are unique to each person including:

Irregular periods or no periods at all – with PMOS, the ovaries don’t always release an egg each month. This can make periods unpredictable, very light, very heavy, or sometimes stop them altogether.

Hair thinning or hair loss – higher levels of certain hormones (androgens) can cause the hair on your head to become thinner, similar to male-pattern hair loss.

Oily skin or acne – hormone imbalances can make the skin produce more oil, which often leads to breakouts, especially on the face, chest, and back.

Excessive hair growth – extra androgens can also cause hair to grow in areas like the face, chest, stomach, or back.

Difficulty getting pregnant – irregular or absent ovulation (when an egg is released) makes it harder to conceive naturally.

Weight gain – many women with PMOS find they put on weight easily or struggle to lose it, often linked to insulin resistance.

What Are The Different Types of PMOS?

Inflammatory PMOS – Linked to low-level inflammation, which can affect hormones, ovulation, and cause symptoms like fatigue, bloating, or skin issues.

Adrenal PMOS – Often triggered by stress, leading to higher “male” hormone levels and symptoms like excess hair, acne, or irregular periods.

Insulin-Resistant PMOS – The most common type, where the body struggles to use insulin properly, increasing androgens and causing weight gain, hair growth, acne, and irregular cycles.

Supporting PMOS

Navigating PMOS doesn’t have to be difficult so ensuring you get the correct help is super important in understanding PMOS and how to support it.

Consult With a GP

Of course speaking with a doctor about your symptoms and whether or not you might have PMOS is important to find out the steps you need to take to support yourself and whether you have PMOS.

For PMOS, treatment around fertility might involve medications. It’s important to speak with your GP or a specialist. They can guide you through the options that may best suit your symptoms and overall health.

Balanced Diet

Insulin resistance is common in PMOS which means your cells don’t respond well to insulin and therefore your body makes more of it. Extra insulin causes more testosterone, hormone imbalance, irregular periods, inflammation and weight gain.

Managing insulin can help reduce symptoms, regulate your cycle, and improve your overall hormone health. And certain nutrients can support your body naturally which we discuss below.

Did you know there are 5 nutrients to support PMOS?

🫘Myo-Inositol

Function: improves insulin sensitivity and supports healthy weight

Found in: Whole grains, beans, nuts, and fruit

🌱Berberine

Function: Lowers blood sugar and boosts insulin sensitivity

Found in: Natural plant compound

☀️Vitamin D

Function: Increases insulin sensitivity and lowers androgen levels

Found in: Sunlight, eggs, mushrooms

🥕Chromium

Function: Helps insulin work better and supports stable blood sugar

Found in: Whole grains, nuts and seeds, fruits, and vegetables

🥩Alpha Lipoic Acid (ALA)

Function: Improves insulin function and reduces inflammation

Found in: Red meat, vegetables (small levels of ALA)

Regular Exercise

Exercise plays a big role in managing PMOS. It helps the body use insulin more effectively, which means blood sugar levels stay more stable. This can reduce the overproduction of insulin that often drives hormone imbalances in PMOS. Regular movement also supports weight management by boosting metabolism and burning calories, making it easier to maintain a healthy weight.

Different types of exercise that you could try include: strength training, cardio, high-intensity interval training, yoga, pilates, or low-impact movement.

Talk to Loved Ones

Opening up to the people you love about PMOS can really help. When you share what you’re going through, it takes some of the pressure off and reminds you that you don’t have to deal with the symptoms on your own.

Useful Links

Verity UK – UK charity that raises awareness around PMOS.

PCOS Awareness Association – Organisation creating worldwide awareness of PMOS helping those get a diagnose, recieve the right information, and support.

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